elp4 protein (Takifugu rubripes) - STRING interaction network

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Score

elp4

Elongator acetyltransferase complex subunit 4. (408 aa)

Predicted Functional Partners:

elp1

0.997

elp6

0.997

elp3

0.996

elp2

0.995

elp5

0.995

pipox

0.948

mocs3

0.877

urm1

0.812

ciao2b

0.761

immp1l

0.753

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ciao2b	elp4	ENSTRUP00000025858	ENSTRUP00000017660	Cytosolic iron-sulfur assembly component 2B.	Elongator acetyltransferase complex subunit 4.	0.761
ciao2b	elp5	ENSTRUP00000025858	ENSTRUP00000028796	Cytosolic iron-sulfur assembly component 2B.	Elongator acetyltransferase complex subunit 5.	0.801
elp1	elp2	ENSTRUP00000004322	ENSTRUP00000027989	Uncharacterized protein.	Elongator acetyltransferase complex subunit 2.	0.996
elp1	elp3	ENSTRUP00000004322	ENSTRUP00000007288	Uncharacterized protein.	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.	0.998
elp1	elp4	ENSTRUP00000004322	ENSTRUP00000017660	Uncharacterized protein.	Elongator acetyltransferase complex subunit 4.	0.997
elp1	elp5	ENSTRUP00000004322	ENSTRUP00000028796	Uncharacterized protein.	Elongator acetyltransferase complex subunit 5.	0.975
elp1	elp6	ENSTRUP00000004322	ENSTRUP00000004790	Uncharacterized protein.	Elongator acetyltransferase complex subunit 6.	0.979
elp1	mocs3	ENSTRUP00000004322	ENSTRUP00000021774	Uncharacterized protein.	Adenylyltransferase and sulfurtransferase MOCS3; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...]	0.863
elp1	urm1	ENSTRUP00000004322	ENSTRUP00000021380	Uncharacterized protein.	Ubiquitin-related modifier 1; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically [...]	0.733
elp2	elp1	ENSTRUP00000027989	ENSTRUP00000004322	Elongator acetyltransferase complex subunit 2.	Uncharacterized protein.	0.996
elp2	elp3	ENSTRUP00000027989	ENSTRUP00000007288	Elongator acetyltransferase complex subunit 2.	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.	0.997
elp2	elp4	ENSTRUP00000027989	ENSTRUP00000017660	Elongator acetyltransferase complex subunit 2.	Elongator acetyltransferase complex subunit 4.	0.995
elp2	elp5	ENSTRUP00000027989	ENSTRUP00000028796	Elongator acetyltransferase complex subunit 2.	Elongator acetyltransferase complex subunit 5.	0.984
elp2	elp6	ENSTRUP00000027989	ENSTRUP00000004790	Elongator acetyltransferase complex subunit 2.	Elongator acetyltransferase complex subunit 6.	0.984
elp3	elp1	ENSTRUP00000007288	ENSTRUP00000004322	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.	Uncharacterized protein.	0.998
elp3	elp2	ENSTRUP00000007288	ENSTRUP00000027989	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.	Elongator acetyltransferase complex subunit 2.	0.997
elp3	elp4	ENSTRUP00000007288	ENSTRUP00000017660	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.	Elongator acetyltransferase complex subunit 4.	0.996
elp3	elp5	ENSTRUP00000007288	ENSTRUP00000028796	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.	Elongator acetyltransferase complex subunit 5.	0.983
elp3	elp6	ENSTRUP00000007288	ENSTRUP00000004790	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.	Elongator acetyltransferase complex subunit 6.	0.984
elp3	mocs3	ENSTRUP00000007288	ENSTRUP00000021774	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.	Adenylyltransferase and sulfurtransferase MOCS3; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...]	0.849