Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
aqp11Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. (271 aa)    
Predicted Functional Partners:
LOC101063737
Aquaporin 10b; Belongs to the MIP/aquaporin (TC 1.A.8) family.
     
 0.719
aqp8
Aquaporin 8b; Belongs to the MIP/aquaporin (TC 1.A.8) family.
     
 0.696
sumo1
Small ubiquitin-related modifier.
   
 0.671
sumo2
Small ubiquitin-related modifier.
   
 0.671
LOC101063780
Small ubiquitin-related modifier 3.
   
 0.671
LOC101073277
Small ubiquitin-related modifier.
   
 0.671
uba2
SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.
    
 
 0.644
LOC101068606
SUMO specific peptidase 3b.
   
 0.608
senp5
ULP_PROTEASE domain-containing protein.
   
 0.608
ENSTRUP00000050485
annotation not available
   
 0.608
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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