close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101067369Growth factor receptor bound protein 7. (497 aa)    
Predicted Functional Partners:
LOC101074430
Tyrosine-protein kinase receptor.
    
 0.584
LOC101079603
Tyrosine-protein kinase receptor.
    
 0.584
LOC101063427
Tyrosine-protein kinase receptor.
    
 0.584
LOC101074083
Tyrosine-protein kinase receptor.
    
 0.584
crkl
V-crk avian sarcoma virus CT10 oncogene homolog-like.
    
 0.574
ret
Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.
    
 0.574
LOC101065989
CRK proto-oncogene, adaptor protein.
    
 0.540
grb2
Growth factor receptor-bound protein 2b.
    
 0.533
LOC101061204
Uncharacterized protein.
    
 0.533
tie1
Tyrosine kinase with immunoglobulin-like and EGF-like domains 1.
   
  0.516
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
Server load: low (20%) [HD]