close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PACS1Phosphofurin acidic cluster sorting protein 1a. (905 aa)    
Predicted Functional Partners:
WDR37
WD repeat domain 37.
    
 
 0.626
LOC101078020
WD repeat domain 37.
    
 
 0.626
tox4
TOX high mobility group box family member 4 b.
      
 0.621
LOC101078322
Furin (paired basic amino acid cleaving enzyme) a; Belongs to the peptidase S8 family.
    
 
 0.565
LOC101061571
Furin (paired basic amino acid cleaving enzyme) b; Belongs to the peptidase S8 family.
    
 
 0.565
H2SK46_TAKRU
FOP_dimer domain-containing protein.
    
   0.483
alk
Tyrosine-protein kinase receptor.
      
 0.429
SMURF2
E3 ubiquitin-protein ligase.
      
 0.428
LOC101071114
E3 ubiquitin-protein ligase.
      
 0.428
smad7
Mothers against decapentaplegic homolog.
      
 0.426
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
Server load: low (18%) [HD]