Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
got1Aspartate aminotransferase. (444 aa)    
Predicted Functional Partners:
got2
Aspartate aminotransferase.
  
 
0.987
mdh1
Malate dehydrogenase.
   
 0.975
LOC101072315
Malate dehydrogenase.
   
 0.975
asns
Asparagine synthetase [glutamine-hydrolyzing].
   
 0.973
LOC101072881
Glutamate dehydrogenase 1b; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 0.972
fh
Fumarate hydratase.
   
 0.970
hpd
4-hydroxyphenylpyruvate dioxygenase.
  
 
 0.970
tat
Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate.
   
 0.968
ldhb
L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
   
 0.965
LOC101079446
L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
   
 0.965
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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