Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
frmd6FERM domain containing 6. (616 aa)    
Predicted Functional Partners:
yap1
Yes-associated protein 1.
   
 0.970
fbxw11
F-box and WD repeat domain containing 11b.
    
 
 0.887
ZADH2
Zinc binding alcohol dehydrogenase domain containing 2.
      
 0.871
lats1
Large tumor suppressor kinase 1.
    
 
 0.825
lats2
Large tumor suppressor kinase 2.
    
 
 0.824
LOC101070153
Si:ch1073-186i23.1; Belongs to the G-protein coupled receptor 2 family.
    
   0.807
LOC101071242
Interleukin 10 receptor, beta.
   
 
 0.807
ENSTRUP00000061068
annotation not available
    
   0.807
ENSTRUP00000062576
annotation not available
    
   0.807
ADGRL3
Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.
    
   0.807
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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