close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
plekhf2Pleckstrin homology domain containing, family F (with FYVE domain) member 2. (246 aa)    
Predicted Functional Partners:
plekhh2
Pleckstrin homology domain containing, family H (with MyTH4 domain) member 2.
      
 0.565
micu1
Mitochondrial calcium uptake 1.
   
 0.552
neurl1b
Neuralized E3 ubiquitin protein ligase 1B.
      
 0.540
fam43a
Family with sequence similarity 43 member A.
      
 0.532
smdt1
Single-pass membrane protein with aspartate-rich tail 1a.
     
 0.485
smdt1-2
Single-pass membrane protein with aspartate-rich tail 1b.
     
 0.485
MCUB
Mitochondrial calcium uniporter dominant negative beta subunit.
     
 0.476
mcu
Mitochondrial calcium uniporter.
     
 0.476
snx29
Sorting nexin 29.
    
 
 0.472
PLEKHG1
Pleckstrin homology and RhoGEF domain containing G1.
      
 0.434
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
Server load: low (18%) [HD]