| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ENSTRUP00000053968 | cdc45 | ENSTRUP00000053968 | ENSTRUP00000042171 | Uncharacterized protein. | CDC45 cell division cycle 45 homolog (S. cerevisiae). | 0.989 |
| ENSTRUP00000053968 | cdc6 | ENSTRUP00000053968 | ENSTRUP00000085004 | Uncharacterized protein. | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | 0.982 |
| ENSTRUP00000053968 | mcm2 | ENSTRUP00000053968 | ENSTRUP00000018075 | Uncharacterized protein. | DNA helicase; Belongs to the MCM family. | 0.994 |
| ENSTRUP00000053968 | mcm3 | ENSTRUP00000053968 | ENSTRUP00000059130 | Uncharacterized protein. | DNA helicase; Belongs to the MCM family. | 0.995 |
| ENSTRUP00000053968 | mcm5 | ENSTRUP00000053968 | ENSTRUP00000055666 | Uncharacterized protein. | DNA helicase; Belongs to the MCM family. | 0.995 |
| ENSTRUP00000053968 | mcm6 | ENSTRUP00000053968 | ENSTRUP00000086190 | Uncharacterized protein. | DNA helicase; Belongs to the MCM family. | 0.997 |
| ENSTRUP00000053968 | mcm7 | ENSTRUP00000053968 | ENSTRUP00000084916 | Uncharacterized protein. | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.997 |
| ENSTRUP00000053968 | orc1 | ENSTRUP00000053968 | ENSTRUP00000009155 | Uncharacterized protein. | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | 0.980 |
| ENSTRUP00000053968 | pola1 | ENSTRUP00000053968 | ENSTRUP00000019793 | Uncharacterized protein. | DNA polymerase. | 0.974 |
| cdc45 | ENSTRUP00000053968 | ENSTRUP00000042171 | ENSTRUP00000053968 | CDC45 cell division cycle 45 homolog (S. cerevisiae). | Uncharacterized protein. | 0.989 |
| cdc45 | cdc6 | ENSTRUP00000042171 | ENSTRUP00000085004 | CDC45 cell division cycle 45 homolog (S. cerevisiae). | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | 0.962 |
| cdc45 | mcm2 | ENSTRUP00000042171 | ENSTRUP00000018075 | CDC45 cell division cycle 45 homolog (S. cerevisiae). | DNA helicase; Belongs to the MCM family. | 0.998 |
| cdc45 | mcm3 | ENSTRUP00000042171 | ENSTRUP00000059130 | CDC45 cell division cycle 45 homolog (S. cerevisiae). | DNA helicase; Belongs to the MCM family. | 0.994 |
| cdc45 | mcm4 | ENSTRUP00000042171 | ENSTRUP00000088032 | CDC45 cell division cycle 45 homolog (S. cerevisiae). | DNA helicase; Belongs to the MCM family. | 0.989 |
| cdc45 | mcm5 | ENSTRUP00000042171 | ENSTRUP00000055666 | CDC45 cell division cycle 45 homolog (S. cerevisiae). | DNA helicase; Belongs to the MCM family. | 0.997 |
| cdc45 | mcm6 | ENSTRUP00000042171 | ENSTRUP00000086190 | CDC45 cell division cycle 45 homolog (S. cerevisiae). | DNA helicase; Belongs to the MCM family. | 0.997 |
| cdc45 | mcm7 | ENSTRUP00000042171 | ENSTRUP00000084916 | CDC45 cell division cycle 45 homolog (S. cerevisiae). | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.995 |
| cdc45 | orc1 | ENSTRUP00000042171 | ENSTRUP00000009155 | CDC45 cell division cycle 45 homolog (S. cerevisiae). | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | 0.992 |
| cdc45 | pola1 | ENSTRUP00000042171 | ENSTRUP00000019793 | CDC45 cell division cycle 45 homolog (S. cerevisiae). | DNA polymerase. | 0.988 |
| cdc6 | ENSTRUP00000053968 | ENSTRUP00000085004 | ENSTRUP00000053968 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | Uncharacterized protein. | 0.982 |
