Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC101064442Zmp:0000001088; Belongs to the peptidase S1 family. (279 aa)    
Predicted Functional Partners:
LOC101078447
Amyloid-beta A4 protein; Functional neuronal receptor which couples to intracellular signaling pathway through the GTP-binding protein G(O); Belongs to the APP family.
    
 0.753
APP
Amyloid beta precursor protein.
    
 0.750
H2SV07_TAKRU
Coagulation factor II (thrombin) receptor-like 2.
    
  0.743
LOC101078077
Coagulation factor II (thrombin) receptor-like 1, tandem duplicate 1.
    
 0.742
LOC101064847
Coagulation factor II (thrombin) receptor-like 1, tandem duplicate 2.
    
 0.742
F2RL2
Coagulation factor II thrombin receptor like 2.
    
 0.736
f2r
Coagulation factor II (thrombin) receptor; Belongs to the G-protein coupled receptor 1 family.
    
  0.716
LOC101078065
Tissue factor pathway inhibitor.
    
 0.706
spint1
Serine peptidase inhibitor, Kunitz type 1 a.
   
 0.694
LOC101074356
Zgc:112160; Belongs to the peptidase S1 family.
  
0.657
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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