Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
H2T0D0_TAKRUSi:ch211-167j9.5. (416 aa)    
Predicted Functional Partners:
scf
Uncharacterized protein.
    
 0.826
plcg2
Phosphoinositide phospholipase C.
    
 0.766
plcg1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
    
 0.766
LOC101065481
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1-like.
    
 0.766
grb2
Growth factor receptor-bound protein 2b.
    
 0.764
LOC101061204
Uncharacterized protein.
    
 0.764
gdnf
Glial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake.
    
 0.759
LOC101067669
PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.
    
 0.756
pdgfb
Platelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family.
    
 0.750
cblb
Cbl proto-oncogene B, E3 ubiquitin protein ligase.
    
  0.748
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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