tmem97 protein (Takifugu rubripes) - STRING interaction network

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tmem97

Transmembrane protein 97; Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cells. Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation. May play a role as a regulator of cellular cholesterol homeostasis. May function as sterol isomerase. May alter the activity of some cytochrome P450 proteins. (201 aa)

Predicted Functional Partners:

sigmar1

0.754

smim4

0.704

tmem94

0.663

LOC101071420

0.625

pgrmc1

0.614

ldah

0.597

slc14a1

0.593

IQCA1L

0.587

guk1

0.561

LOC101075329

0.561

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
IQCA1L	tmem97	ENSTRUP00000056587	ENSTRUP00000018148	ATPase_AAA_core domain-containing protein.	Transmembrane protein 97; Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cells. Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation. May play a role as a regulator of cellular cholesterol homeostasis. May function as sterol isomerase. May alter the activity of some cytochrome P450 proteins.	0.587
LOC101071420	tmem97	ENSTRUP00000069845	ENSTRUP00000018148	BSD domain containing 1.	Transmembrane protein 97; Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cells. Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation. May play a role as a regulator of cellular cholesterol homeostasis. May function as sterol isomerase. May alter the activity of some cytochrome P450 proteins.	0.625
LOC101075329	guk1	ENSTRUP00000080612	ENSTRUP00000036929	Guanylate kinase 1b.	Guanylate kinase 1a.	0.901
LOC101075329	tmem97	ENSTRUP00000080612	ENSTRUP00000018148	Guanylate kinase 1b.	Transmembrane protein 97; Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cells. Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation. May play a role as a regulator of cellular cholesterol homeostasis. May function as sterol isomerase. May alter the activity of some cytochrome P450 proteins.	0.561
guk1	LOC101075329	ENSTRUP00000036929	ENSTRUP00000080612	Guanylate kinase 1a.	Guanylate kinase 1b.	0.901
guk1	tmem97	ENSTRUP00000036929	ENSTRUP00000018148	Guanylate kinase 1a.	Transmembrane protein 97; Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cells. Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation. May play a role as a regulator of cellular cholesterol homeostasis. May function as sterol isomerase. May alter the activity of some cytochrome P450 proteins.	0.561
ldah	smim4	ENSTRUP00000001381	ENSTRUP00000064189	Lipid droplet associated hydrolase.	Small integral membrane protein 4.	0.757
ldah	tmem97	ENSTRUP00000001381	ENSTRUP00000018148	Lipid droplet associated hydrolase.	Transmembrane protein 97; Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cells. Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation. May play a role as a regulator of cellular cholesterol homeostasis. May function as sterol isomerase. May alter the activity of some cytochrome P450 proteins.	0.597
pgrmc1	sigmar1	ENSTRUP00000013364	ENSTRUP00000049523	Progesterone receptor membrane component 1; Belongs to the cytochrome b5 family.	Sigma non-opioid intracellular receptor 1.	0.453
pgrmc1	tmem97	ENSTRUP00000013364	ENSTRUP00000018148	Progesterone receptor membrane component 1; Belongs to the cytochrome b5 family.	Transmembrane protein 97; Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cells. Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation. May play a role as a regulator of cellular cholesterol homeostasis. May function as sterol isomerase. May alter the activity of some cytochrome P450 proteins.	0.614
sigmar1	pgrmc1	ENSTRUP00000049523	ENSTRUP00000013364	Sigma non-opioid intracellular receptor 1.	Progesterone receptor membrane component 1; Belongs to the cytochrome b5 family.	0.453
sigmar1	tmem97	ENSTRUP00000049523	ENSTRUP00000018148	Sigma non-opioid intracellular receptor 1.	Transmembrane protein 97; Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cells. Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation. May play a role as a regulator of cellular cholesterol homeostasis. May function as sterol isomerase. May alter the activity of some cytochrome P450 proteins.	0.754
slc14a1	tmem97	ENSTRUP00000026150	ENSTRUP00000018148	Urea transporter; Belongs to the urea transporter family.	Transmembrane protein 97; Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cells. Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation. May play a role as a regulator of cellular cholesterol homeostasis. May function as sterol isomerase. May alter the activity of some cytochrome P450 proteins.	0.593
smim4	ldah	ENSTRUP00000064189	ENSTRUP00000001381	Small integral membrane protein 4.	Lipid droplet associated hydrolase.	0.757
smim4	tmem97	ENSTRUP00000064189	ENSTRUP00000018148	Small integral membrane protein 4.	Transmembrane protein 97; Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cells. Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation. May play a role as a regulator of cellular cholesterol homeostasis. May function as sterol isomerase. May alter the activity of some cytochrome P450 proteins.	0.704
tmem94	tmem97	ENSTRUP00000016412	ENSTRUP00000018148	Transmembrane protein 94.	Transmembrane protein 97; Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cells. Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation. May play a role as a regulator of cellular cholesterol homeostasis. May function as sterol isomerase. May alter the activity of some cytochrome P450 proteins.	0.663
tmem97	IQCA1L	ENSTRUP00000018148	ENSTRUP00000056587	Transmembrane protein 97; Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cells. Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation. May play a role as a regulator of cellular cholesterol homeostasis. May function as sterol isomerase. May alter the activity of some cytochrome P450 proteins.	ATPase_AAA_core domain-containing protein.	0.587
tmem97	LOC101071420	ENSTRUP00000018148	ENSTRUP00000069845	Transmembrane protein 97; Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cells. Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation. May play a role as a regulator of cellular cholesterol homeostasis. May function as sterol isomerase. May alter the activity of some cytochrome P450 proteins.	BSD domain containing 1.	0.625
tmem97	LOC101075329	ENSTRUP00000018148	ENSTRUP00000080612	Transmembrane protein 97; Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cells. Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation. May play a role as a regulator of cellular cholesterol homeostasis. May function as sterol isomerase. May alter the activity of some cytochrome P450 proteins.	Guanylate kinase 1b.	0.561
tmem97	guk1	ENSTRUP00000018148	ENSTRUP00000036929	Transmembrane protein 97; Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cells. Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation. May play a role as a regulator of cellular cholesterol homeostasis. May function as sterol isomerase. May alter the activity of some cytochrome P450 proteins.	Guanylate kinase 1a.	0.561

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