Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pla2g15Phospholipase A2, group XV. (421 aa)    
Predicted Functional Partners:
LOC101076141
Patatin-like phospholipase domain containing 6.
     
 0.935
lypla1
Lysophospholipase 1.
     
 0.929
LOC105418815
Uncharacterized protein.
     
 0.924
pparg
Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]
     
 0.910
ppard
Uncharacterized protein.
     
 0.908
gpcpd1
Glycerophosphocholine phosphodiesterase 1.
     
 0.905
lcat
Lecithin-cholesterol acyltransferase.
  
  
0.905
PLA2G12B
Phospholipase A2 group XIIB.
   
 
 0.870
pla2g3
Phospholipase A2 group III.
     
 0.860
apoA-IV4
Apolipoprotein A-IV4.
   
 0.854
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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