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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VAV3Si:ch73-383g2.1. (830 aa)    
Predicted Functional Partners:
RAC1
Uncharacterized protein.
   
 0.813
ENSTRUP00000053105
Lymphocyte cytosolic protein 2a.
   
 0.766
grb2
Growth factor receptor-bound protein 2b.
    
0.759
LOC101061204
Uncharacterized protein.
    
0.759
syk
Tyrosine-protein kinase.
   
 0.758
zap70
Tyrosine-protein kinase.
   
 0.670
LOC101073733
Uncharacterized protein.
   
 0.649
LOC101067723
Cell division cycle 42.
   
 0.649
LOC101067160
Rac family small GTPase 1b.
   
 0.628
ENSTRUP00000064457
Ras-related C3 botulinum toxin substrate 3 isoform X1.
   
 0.628
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.