Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
VAV3Si:ch73-383g2.1. (830 aa)    
Predicted Functional Partners:
RAC1
Uncharacterized protein.
   
 0.977
LOC101067160
Rac family small GTPase 1b.
   
 0.967
ENSTRUP00000053105
Lymphocyte cytosolic protein 2a.
   
 0.888
grb2
Growth factor receptor-bound protein 2b.
    
 0.827
LOC101061204
Uncharacterized protein.
    
 0.827
LOC101063692
Phosphoinositide-3-kinase, regulatory subunit 2 (beta).
    
 
0.802
LOC101065244
Uncharacterized protein.
    
 
0.802
pik3r3
Phosphoinositide-3-kinase, regulatory subunit 3b (gamma).
    
 
0.802
LOC101062512
Phosphoinositide-3-kinase, regulatory subunit 1 (alpha).
    
 
0.802
syk
Tyrosine-protein kinase.
   
 0.794
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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