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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101078272BTB (POZ) domain containing 2b. (564 aa)    
Predicted Functional Partners:
cul3
Cullin 3a; Belongs to the cullin family.
   
 0.764
cops3
COP9 signalosome subunit 3.
    
 0.700
cops2
COP9 signalosome subunit 2.
   
  0.694
arfgef1-2
ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited).
    
  0.672
COPS6
COP9 signalosome subunit 6.
    
  0.617
cops8
COP9 signalosome subunit 8.
    
  0.577
cacul1
Cullin domain-containing protein; Belongs to the cullin family.
   
 0.569
cops4
COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis).
    
  0.567
UBA3
Ubiquitin like modifier activating enzyme 3.
   
 
  0.566
ppp1r42
Protein phosphatase 1, regulatory subunit 42.
    
  0.560
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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