Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ccne2Cyclin E2; Belongs to the cyclin family. (416 aa)    
Predicted Functional Partners:
cdk2
Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily.
   
 0.980
rbl1
Retinoblastoma-like 1 (p107).
   
 0.974
LOC101070901
Retinoblastoma-like 2 (p130).
   
 0.974
LOC115246431
Retinoblastoma 1.
   
 0.974
LOC105417819
Cyclin-dependent kinase inhibitor 1A.
   
 0.968
LOC101079162
Cyclin-dependent kinase inhibitor 1D.
   
 0.966
skp2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase.
   
 0.937
LOC101069671
Cyclin-dependent kinase inhibitor 1Cb.
   
 0.882
ENSTRUP00000050866
Uncharacterized protein.
   
 0.882
cdkn1b
Cyclin-dependent kinase inhibitor 1Bb.
   
 0.882
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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