STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ube2fUbiquitin-conjugating enzyme E2F (putative); Belongs to the ubiquitin-conjugating enzyme family. (184 aa)    
Predicted Functional Partners:
ubxn7
UBX domain protein 7.
   
 
 0.926
UBXN7
UBX domain protein 7.
   
 
 0.926
UBA3
Ubiquitin like modifier activating enzyme 3.
    
 0.916
nae1
NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.
    
 0.893
cul3
Cullin 3a; Belongs to the cullin family.
    
 0.890
LOC115248454
RING-box protein 1.
    
 0.840
LOC101079814
Ring-box 1, E3 ubiquitin protein ligase.
    
 0.840
LOC101077379
NEDD8 ubiquitin like modifier.
   
 0.840
H2SH60_TAKRU
Ubiquitin-like domain-containing protein.
   
 0.840
uba5
Ubiquitin-like modifier activating enzyme 5.
    
 0.838
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
Server load: low (28%) [HD]