Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC101075168TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (234 aa)    
Predicted Functional Partners:
tnfrsf13b
TNFR-Cys domain-containing protein.
  
 
 0.936
aktip
Akt interacting protein.
    
   0.728
LOC101067698
Cystatin domain-containing protein.
    
 
 0.633
LOC105419466
Cystatin domain-containing protein; Belongs to the cystatin family.
    
 
 0.633
tnfsf12
TNF superfamily member 12; Belongs to the tumor necrosis factor family.
    
 0.627
LOC101068020
CD40 ligand; Belongs to the tumor necrosis factor family.
     
 0.612
LOC101080086
TNF superfamily member 11; Belongs to the tumor necrosis factor family.
    
 0.590
LOC101073524
Tumor necrosis factor receptor superfamily member 11A isoform X2.
     
 0.510
LOC101068369
Mitogen-activated protein kinase kinase kinase 14a.
     
 0.492
LOC101067596
Mitogen-activated protein kinase kinase kinase 14.
     
 0.492
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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