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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101075168TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (234 aa)    
Predicted Functional Partners:
tnfrsf13b
TNFR-Cys domain-containing protein.
  
 
 0.912
LOC101068020
CD40 ligand; Belongs to the tumor necrosis factor family.
   
 
 0.694
LOC101080086
TNF superfamily member 11; Belongs to the tumor necrosis factor family.
   
 0.655
tnfsf12
TNF superfamily member 12; Belongs to the tumor necrosis factor family.
   
 0.645
LOC101073524
Tumor necrosis factor receptor superfamily member 11A isoform X2.
     
 0.604
cd40
CD40.
   
 0.580
tnfrsf14
Tumor necrosis factor receptor superfamily, member 1B.
   
 
 0.554
LOC101073138
Uncharacterized protein.
   
 0.538
ENSTRUP00000066347
Tumor necrosis factor receptor superfamily member 5-like.
   
 0.538
LOC101068369
Mitogen-activated protein kinase kinase kinase 14a.
     
 0.532
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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