Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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LOC101077436Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. (485 aa)    
Predicted Functional Partners:
LOC101077059
Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.
   
 0.915
LOC101078548
Mitogen-activated protein kinase.
   
 0.869
LOC101073984
CREB binding protein a.
   
 0.799
junb
JunB protein.
   
 0.792
LOC101078177
Proto-oncogene c-Fos; Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. FOS has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation (By similarity).
    
 0.792
fosl2
Fos-like antigen 2.
    
 0.752
LOC101073575
Mitogen-activated protein kinase.
   
 0.740
LOC101070190
Mitogen-activated protein kinase.
   
 0.740
mapk10
Mitogen-activated protein kinase.
   
 0.740
JUND
BZIP domain-containing protein.
   
 0.732
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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