Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC101064958Hydroxysteroid (11-beta) dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (453 aa)    
Predicted Functional Partners:
LOC101075863
Cytochrome P450, family 11, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family.
    
 0.979
hsd3b1
Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1; Belongs to the 3-beta-HSD family.
     
 0.935
AKR1D1
Aldo-keto reductase family 1 member D1.
   
 
 0.930
hsd11b1l
Hydroxysteroid (11-beta) dehydrogenase 1-like a.
  
 
0.930
nr3c2
Nuclear receptor subfamily 3, group C, member 2.
   
 
 0.772
hsd17b3
Hydroxysteroid (17-beta) dehydrogenase 3.
      
 0.724
h6pd
Hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase).
   
  
 0.720
LOC101062852
Nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor).
    
 
 0.715
LOC101064982
Proopiomelanocortin.
      
 0.707
pfcyp19a
Uncharacterized protein; Belongs to the cytochrome P450 family.
    
 
 0.700
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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