Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
tcf15Transcription factor 15. (180 aa)    
Predicted Functional Partners:
meox1
Mesenchyme homeobox 1.
    
 
 0.634
LOC101078665
Fork-head domain-containing protein.
    
 0.547
tnmd
Tenomodulin.
      
 0.494
LOC101070955
T-box transcription factor 6.
    
 0.487
herc2
HECT and RLD domain containing E3 ubiquitin protein ligase 2.
    
 0.455
DMD
Dystrophin; May play a role in anchoring the cytoskeleton to the plasma membrane.
      
 0.453
LOC101064488
Utrophin; May play a role in anchoring the cytoskeleton to the plasma membrane.
      
 0.438
smc6
Structural maintenance of chromosomes protein 6; Core component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination and mediates sumoylation of shelterin complex (telosome) components (By similarity).
      
 0.437
dvl3
Dishevelled segment polarity protein 3a.
    
 
 0.434
mib2
Mindbomb E3 ubiquitin protein ligase 2.
      
 0.434
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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