Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mis18aMIS18 kinetochore protein A. (212 aa)    
Predicted Functional Partners:
oip5
Mis18 domain-containing protein.
   
 0.999
cenpq
Uncharacterized protein.
   
 
 0.896
LOC101074167
WD_REPEATS_REGION domain-containing protein.
    
 0.891
rbbp4
Retinoblastoma binding protein 4.
    
 0.891
cenpk
Centromere protein K.
   
 
 0.873
cenpn
Centromere protein N.
   
 
 0.864
cenpt
Uncharacterized protein.
   
 
 0.825
wdr73
Uncharacterized protein.
    
 0.821
cenpw
Uncharacterized protein.
   
 
 0.803
cenpi
Centromere protein I.
   
 
 0.763
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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