Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC101064580TLE family member 2, transcriptional corepressor a. (804 aa)    
Predicted Functional Partners:
rbpj
Recombination signal binding protein for immunoglobulin kappa J region.
    
 0.926
rbpjl
Recombining binding protein suppressor of hairless-like protein isoform X1.
    
 0.925
LOC101072042
Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
    
 0.921
HDAC2
Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
    
 0.921
lef1
Lymphoid enhancer-binding factor 1.
    
 0.893
tcf7l2
Transcription factor 7 like 2.
    
 0.850
LOC101074632
HMG box domain-containing protein.
    
 0.849
tcf7l1
Transcription factor 7 like 1b.
    
 0.849
LOC115251054
Lymphoid enhancer-binding factor 1-like isoform X1.
    
 0.849
tcf7
Transcription factor 7.
    
 0.849
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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