Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-expression
Experiments
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[Homology]
Score
LOC101076161Rhomboid domain-containing protein. (376 aa)    
Predicted Functional Partners:
pink1
PTEN induced kinase 1.
    
 
 0.815
LOC101069326
YME1-like 1b.
   
 
 0.716
yme1l1
YME1-like 1a.
   
 
 0.716
timm13
Translocase of inner mitochondrial membrane 13 homolog (yeast); Belongs to the small Tim family.
      
 0.695
phb2
Prohibitin.
   
 0.647
LOC101071475
Cytochrome c oxidase assembly homolog 11 (yeast).
   
  
 0.633
timm8a
Mitochondrial import inner membrane translocase subunit Tim8 A; Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIMM8- TIMM13 complex mediates the import of some pro [...]
      
 0.633
prkn
Ubiquitin-like domain-containing protein.
    
 
 0.629
TIMM22
Translocase of inner mitochondrial membrane 22.
      
 0.626
ndufb7
NADH:ubiquinone oxidoreductase subunit B7.
      
 0.626
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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