Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hpse2Heparanase 2. (593 aa)    
Predicted Functional Partners:
hpse
Heparanase.
  
  
 
0.903
LOC101066362
Iduronate 2-sulfatase.
     
 0.900
LOC101065464
Leucine-rich repeats and immunoglobulin-like domains 2.
      
 0.699
LOC101063580
Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.
     
 0.619
SDC3
Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.
     
 0.559
LOC101079000
Glypican 5a; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
     
 0.544
LOC101074197
Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
     
 0.530
gpc4
Glypican 4; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
     
 0.527
LOC101067285
Glypican 5c; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
     
 0.527
LOC101067728
Glypican-5-like.
     
 0.527
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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