SELE protein (Takifugu rubripes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

SELE

Selectin P. (534 aa)

Predicted Functional Partners:

LOC101077330

0.856

cd44

0.818

LOC101063965

0.677

LOC101075456

0.677

cd63

0.657

LOC101065923

0.649

snx17

0.633

LOC101071548

0.539

ap2m1

0.522

Tnc

0.512

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101063965	LOC101075456	ENSTRUP00000038547	ENSTRUP00000042299	Golgi glycoprotein 1b.	Golgi glycoprotein 1a.	0.901
LOC101063965	SELE	ENSTRUP00000038547	ENSTRUP00000019580	Golgi glycoprotein 1b.	Selectin P.	0.677
LOC101065923	LOC101077330	ENSTRUP00000046484	ENSTRUP00000054509	Uncharacterized protein.	Uncharacterized protein.	0.424
LOC101065923	SELE	ENSTRUP00000046484	ENSTRUP00000019580	Uncharacterized protein.	Selectin P.	0.649
LOC101065923	cd44	ENSTRUP00000046484	ENSTRUP00000051098	Uncharacterized protein.	Link domain-containing protein.	0.883
LOC101065923	cd63	ENSTRUP00000046484	ENSTRUP00000081213	Uncharacterized protein.	Tetraspanin.	0.591
LOC101071548	SELE	ENSTRUP00000050557	ENSTRUP00000019580	Uncharacterized protein.	Selectin P.	0.539
LOC101071548	cd44	ENSTRUP00000050557	ENSTRUP00000051098	Uncharacterized protein.	Link domain-containing protein.	0.446
LOC101075456	LOC101063965	ENSTRUP00000042299	ENSTRUP00000038547	Golgi glycoprotein 1a.	Golgi glycoprotein 1b.	0.901
LOC101075456	SELE	ENSTRUP00000042299	ENSTRUP00000019580	Golgi glycoprotein 1a.	Selectin P.	0.677
LOC101077330	LOC101065923	ENSTRUP00000054509	ENSTRUP00000046484	Uncharacterized protein.	Uncharacterized protein.	0.424
LOC101077330	SELE	ENSTRUP00000054509	ENSTRUP00000019580	Uncharacterized protein.	Selectin P.	0.856
LOC101077330	cd44	ENSTRUP00000054509	ENSTRUP00000051098	Uncharacterized protein.	Link domain-containing protein.	0.406
SELE	LOC101063965	ENSTRUP00000019580	ENSTRUP00000038547	Selectin P.	Golgi glycoprotein 1b.	0.677
SELE	LOC101065923	ENSTRUP00000019580	ENSTRUP00000046484	Selectin P.	Uncharacterized protein.	0.649
SELE	LOC101071548	ENSTRUP00000019580	ENSTRUP00000050557	Selectin P.	Uncharacterized protein.	0.539
SELE	LOC101075456	ENSTRUP00000019580	ENSTRUP00000042299	Selectin P.	Golgi glycoprotein 1a.	0.677
SELE	LOC101077330	ENSTRUP00000019580	ENSTRUP00000054509	Selectin P.	Uncharacterized protein.	0.856
SELE	Tnc	ENSTRUP00000019580	ENSTRUP00000055703	Selectin P.	Fibronectin type-III domain-containing protein.	0.512
SELE	ap2m1	ENSTRUP00000019580	ENSTRUP00000068352	Selectin P.	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	0.522