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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TWSG1Twisted gastrulation BMP signaling modulator 1. (218 aa)    
Predicted Functional Partners:
chrd
Chordin.
    
 
 0.754
gdf15
TGF_BETA_2 domain-containing protein.
   
 
 0.582
bmper
BMP binding endothelial regulator.
      
 0.566
LRRC30
Leucine rich repeat containing 30.
   
  
 0.558
bmp2
Bone morphogenetic protein 2b.
   
 
 0.462
bmp4
Bone morphogenetic protein 4.
   
 
 0.462
LOC101069608
Bone morphogenetic protein 16.
   
 
 0.462
disp1
Dispatched homolog 1 (Drosophila).
      
 0.426
rnf43
RING-type domain-containing protein.
   
  
 0.413
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.