Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-expression
Experiments
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[Homology]
Score
dram2DNA-damage regulated autophagy modulator 2b. (269 aa)    
Predicted Functional Partners:
GPR37L1
Nucleolar protein 8.
      
 0.743
LOC101074692
G protein-coupled receptor 37 like 1b.
      
 0.743
ttc12
TPR_REGION domain-containing protein.
      
 0.625
pitpnm3
PITPNM family member 3.
      
 0.611
LOC101071611
PPFIA binding protein 1a.
      
 0.590
dhx40
DEAH (Asp-Glu-Ala-His) box polypeptide 40.
      
 0.579
pter
Phosphotriesterase related.
      
 0.579
LOC101074625
F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
   
  
 0.579
LOC101071691
CTTNBP2 N-terminal like a.
      
 0.571
lrat
Lecithin retinol acyltransferase a.
      
 0.558
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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