Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC101064415Uncharacterized protein; Belongs to the peptidase C14A family. (384 aa)    
Predicted Functional Partners:
il1b
Interleukin-1; Belongs to the IL-1 family.
   
 0.995
LOC101076232
Uncharacterized protein.
   
 0.992
casp8
Uncharacterized protein; Belongs to the peptidase C14A family.
   
0.956
LOC101075191
Uncharacterized protein; Belongs to the peptidase C14A family.
   
0.942
LOC101061322
Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
   
0.937
LOC101062626
Uncharacterized protein; Belongs to the peptidase C14A family.
  
  
 
0.900
il-18
Takifugu rubripes interleukin-18 (il-18), mRNA.
   
 0.894
Il-18
Interleukin-18.
   
 0.893
apaf1
Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.
    
 0.719
gsdme
Gasdermin Eb.
    
 0.685
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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