Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC101077241NK2 homeobox 2a. (273 aa)    
Predicted Functional Partners:
OLIG2
Class B basic helix-loop-helix protein 1/6/7.
   
 0.833
ENSTRUP00000053907
Neurogenin 3.
   
 0.721
prdm8
PR domain containing 8b.
      
 0.657
ptch2
Patched 2.
      
 0.631
neurod1
Neurogenic differentiation factor.
   
 0.620
ENSTRUP00000057273
Oligodendrocyte transcription factor 1.
   
 0.602
shh
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
      
 0.600
ptf1a
Pancreas associated transcription factor 1a.
    
 0.582
LOC101071427
SRY-box transcription factor 10.
   
 
 0.578
pax6
Paired box 6b.
   
 
 0.566
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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