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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
chrna2Cholinergic receptor, nicotinic, alpha 2b (neuronal). (550 aa)    
Predicted Functional Partners:
CHRNA1
Cholinergic receptor nicotinic alpha 1 subunit.
  
0.643
LOC446087
Cholinergic receptor, nicotinic, alpha 1 (muscle).
  
0.643
LOC446016
Cholinergic receptor, nicotinic, beta 3b (neuronal).
  
0.612
LOC446015
Cholinergic receptor, nicotinic, beta polypeptide 3a.
  
0.611
CHRNA5
Cholinergic receptor, nicotinic, alpha 5.
  
0.590
ENSTRUP00000072253
Cholinergic receptor, nicotinic, alpha 5.
  
0.588
ENSTRUP00000070803
Cholinergic receptor, nicotinic, beta 1 (muscle).
  
 
0.587
ENSTRUP00000013993
annotation not available
  
0.576
LOC446026
Cholinergic receptor, nicotinic, beta 1 (muscle).
  
 
0.575
ENSTRUP00000063482
Cholinergic receptor, nicotinic, beta 4 (neuronal).
  
 
0.561
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.