lrig3 protein (Takifugu rubripes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

lrig3

Leucine-rich repeats and immunoglobulin-like domains 3. (1100 aa)

Predicted Functional Partners:

lrig1

0.757

LOC101071528

0.694

mst1r

0.694

met

0.694

COPS6

0.628

rps27a

0.545

cops8

0.531

ret

0.519

hgs

0.512

alk

0.511

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
COPS6	cops8	ENSTRUP00000065015	ENSTRUP00000059629	COP9 signalosome subunit 6.	COP9 signalosome subunit 8.	0.998
COPS6	lrig1	ENSTRUP00000065015	ENSTRUP00000016979	COP9 signalosome subunit 6.	Leucine-rich repeats and immunoglobulin-like domains 1.	0.406
COPS6	lrig3	ENSTRUP00000065015	ENSTRUP00000019934	COP9 signalosome subunit 6.	Leucine-rich repeats and immunoglobulin-like domains 3.	0.628
COPS6	rps27a	ENSTRUP00000065015	ENSTRUP00000027679	COP9 signalosome subunit 6.	Ribosomal protein S27a.	0.780
LOC101071528	hgs	ENSTRUP00000025241	ENSTRUP00000029670	Macrophage stimulating 1 receptor a.	Hepatocyte growth factor-regulated tyrosine kinase substrate.	0.432
LOC101071528	lrig1	ENSTRUP00000025241	ENSTRUP00000016979	Macrophage stimulating 1 receptor a.	Leucine-rich repeats and immunoglobulin-like domains 1.	0.769
LOC101071528	lrig3	ENSTRUP00000025241	ENSTRUP00000019934	Macrophage stimulating 1 receptor a.	Leucine-rich repeats and immunoglobulin-like domains 3.	0.694
LOC101071528	met	ENSTRUP00000025241	ENSTRUP00000078415	Macrophage stimulating 1 receptor a.	Uncharacterized protein.	0.659
LOC101071528	mst1r	ENSTRUP00000025241	ENSTRUP00000035729	Macrophage stimulating 1 receptor a.	Macrophage stimulating 1 receptor b.	0.659
LOC101071528	rps27a	ENSTRUP00000025241	ENSTRUP00000027679	Macrophage stimulating 1 receptor a.	Ribosomal protein S27a.	0.579
alk	lrig1	ENSTRUP00000057849	ENSTRUP00000016979	Tyrosine-protein kinase receptor.	Leucine-rich repeats and immunoglobulin-like domains 1.	0.482
alk	lrig3	ENSTRUP00000057849	ENSTRUP00000019934	Tyrosine-protein kinase receptor.	Leucine-rich repeats and immunoglobulin-like domains 3.	0.511
alk	rps27a	ENSTRUP00000057849	ENSTRUP00000027679	Tyrosine-protein kinase receptor.	Ribosomal protein S27a.	0.425
cops8	COPS6	ENSTRUP00000059629	ENSTRUP00000065015	COP9 signalosome subunit 8.	COP9 signalosome subunit 6.	0.998
cops8	lrig1	ENSTRUP00000059629	ENSTRUP00000016979	COP9 signalosome subunit 8.	Leucine-rich repeats and immunoglobulin-like domains 1.	0.414
cops8	lrig3	ENSTRUP00000059629	ENSTRUP00000019934	COP9 signalosome subunit 8.	Leucine-rich repeats and immunoglobulin-like domains 3.	0.531
cops8	rps27a	ENSTRUP00000059629	ENSTRUP00000027679	COP9 signalosome subunit 8.	Ribosomal protein S27a.	0.696
hgs	LOC101071528	ENSTRUP00000029670	ENSTRUP00000025241	Hepatocyte growth factor-regulated tyrosine kinase substrate.	Macrophage stimulating 1 receptor a.	0.432
hgs	lrig1	ENSTRUP00000029670	ENSTRUP00000016979	Hepatocyte growth factor-regulated tyrosine kinase substrate.	Leucine-rich repeats and immunoglobulin-like domains 1.	0.640
hgs	lrig3	ENSTRUP00000029670	ENSTRUP00000019934	Hepatocyte growth factor-regulated tyrosine kinase substrate.	Leucine-rich repeats and immunoglobulin-like domains 3.	0.512