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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tspan3Tetraspanin. (253 aa)    
Predicted Functional Partners:
idh3a
Isocitrate dehydrogenase [NAD] subunit, mitochondrial.
      
 0.653
igsf8
Immunoglobulin superfamily, member 8.
    
 
 0.483
PCDHAC2
Protocadherin alpha subfamily C, 2.
     
 0.470
GJD2
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
      
 0.459
wnt10a
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
      
 0.457
kcnc2
Potassium voltage-gated channel, Shaw-related subfamily, member 2; Belongs to the potassium channel family.
     
 0.456
LOC101077344
Solute carrier family 7 member 2.
      
 0.455
apoe1
Uncharacterized protein.
      
 0.455
aox1
Aldehyde oxidase 6.
      
 0.454
pmel
Premelanosome protein a.
      
 0.450
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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