close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101074686Toll-like receptor 7; Belongs to the Toll-like receptor family. (1047 aa)    
Predicted Functional Partners:
myd88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
   
 0.984
unc93b1
Unc-93 homolog B1, TLR signaling regulator.
    
 0.939
traf6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.792
LOC101076806
Canopy FGF signaling regulator 3.
    
 0.656
ripk1
Receptor (TNFRSF)-interacting serine-threonine kinase 1, like.
   
 0.655
hsp90b1
Heat shock protein 90, beta (grp94), member 1.
   
 0.655
ptprc
Uncharacterized protein.
   
 0.597
irf7
Interferon regulatory factor 7.
   
 
 0.590
irak4
Interleukin-1 receptor-associated kinase 4.
   
 0.583
LOC101061773
Interleukin-1 receptor-associated kinase 1.
   
 0.579
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.