Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
spartSpartin b. (603 aa)    
Predicted Functional Partners:
ist1
IST1 factor associated with ESCRT-III.
    
 
 0.937
LOC101061475
E3 ubiquitin-protein ligase.
    
 
 0.885
LOC101070007
E3 ubiquitin-protein ligase.
    
 
 0.885
ENSTRUP00000055319
Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family.
      
 0.761
wwp2
E3 ubiquitin-protein ligase.
    
 
 0.744
ENSTRUP00000070181
annotation not available
    
 
 0.744
LOC101068611
WW domain containing E3 ubiquitin protein ligase 1.
    
 
 0.744
tor4a
Torsin family 4, member Aa.
      
 0.725
nipa1
NIPA magnesium transporter 1.
      
 0.721
trim45
Tripartite motif containing 45.
      
 0.710
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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