close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
spartSpartin b. (603 aa)    
Predicted Functional Partners:
ist1
IST1 factor associated with ESCRT-III.
    
 
 0.886
snx15
Sorting nexin 15.
      
 0.660
ENSTRUP00000055319
Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family.
      
 0.645
LOC101061475
E3 ubiquitin-protein ligase.
    
 
 0.643
LOC101070007
E3 ubiquitin-protein ligase.
    
 
 0.643
spg11
Spatacsin_C domain-containing protein.
      
 0.618
spg21
SPG21 abhydrolase domain containing, maspardin.
      
 0.608
tor4a
Torsin family 4, member Aa.
      
 0.576
nipa1
NIPA magnesium transporter 1.
   
  
 0.575
trim45
Tripartite motif containing 45.
      
 0.554
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
Server load: low (40%) [HD]