Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC101063238Striatin interacting protein 1. (840 aa)    
Predicted Functional Partners:
LOC101078365
MOB family member 4, phocein.
    
 
 0.881
slmap
Sarcolemma associated protein.
    
 
 0.866
STRN
Striatin.
   
 
 0.855
pdcd10
Programmed cell death 10b.
    
 
 0.855
H2TJH4_TAKRU
WD_REPEATS_REGION domain-containing protein.
   
 
 0.855
fgfr1op2
FGFR1 oncogene partner 2.
    
 
 0.838
strn3
Striatin, calmodulin binding protein 3.
   
 
 0.827
ppp2r1b
Protein phosphatase 2, regulatory subunit A, beta b.
    
 
 0.823
rnf8
E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]
    
 
 0.794
H2RRN9_TAKRU
Cortactin binding protein 2.
    
 
 0.770
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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