STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
H2T790_TAKRUPellino E3 ubiquitin protein ligase 1. (415 aa)    
Predicted Functional Partners:
irak4
Interleukin-1 receptor-associated kinase 4.
    
 0.869
traf6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.846
LOC101061773
Interleukin-1 receptor-associated kinase 1.
    
 0.824
LOC101068996
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.678
LOC101078382
Ubiquitin-conjugating enzyme E2Na; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.678
ripk1
Receptor (TNFRSF)-interacting serine-threonine kinase 1, like.
    
 0.654
map3k7
Mitogen-activated protein kinase kinase kinase 7.
    
 0.640
ube2v2
Ubiquitin-conjugating enzyme E2 variant 2.
    
 0.620
uxs1
UDP-glucuronate decarboxylase 1.
    
   0.565
ikbkb
Inhibitor of nuclear factor kappa B kinase subunit beta.
   
 0.554
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
Server load: low (24%) [HD]