Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hlcsHolocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase). (907 aa)    
Predicted Functional Partners:
btd
Biotinidase; Catalytic release of biotin from biocytin, the product of biotin-dependent carboxylases degradation.
    
 0.956
PC
Pyruvate carboxylase.
  
 
 0.956
acaca
Acetyl-CoA carboxylase alpha.
  
 0.846
acacb
Acetyl-CoA carboxylase beta.
  
 0.846
nfkbid
ANK_REP_REGION domain-containing protein.
      
 0.833
mccc1
Methylcrotonoyl-CoA carboxylase 1 (alpha).
    
 0.813
LOC101079428
Propionyl-CoA carboxylase subunit alpha.
    
 0.813
mccc2
Methylcrotonoyl-CoA carboxylase 2 (beta).
  
 
 0.789
LOC101062508
Si:ch211-198n5.11.
  
 
 0.789
nelfcd
Negative elongation factor complex member C/D.
    
 0.728
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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