Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
sp4Sp4 transcription factor. (763 aa)    
Predicted Functional Partners:
tmem196
Uncharacterized protein.
      
 0.888
sp1
Sp1 transcription factor.
    
  0.730
itgb8
Integrin beta; Belongs to the integrin beta chain family.
     
 0.610
Ufc1
Ubiquitin-fold modifier-conjugating enzyme 1; E2-like enzyme which forms an intermediate with UFM1 via a thioester linkage.
      
 0.610
ube2i
Ubiquitin-conjugating enzyme E2Ia; Belongs to the ubiquitin-conjugating enzyme family.
    
  0.561
LOC101072687
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
  0.561
hps4
HPS4 biogenesis of lysosomal organelles complex 3 subunit 2.
      
 0.555
pias2
Protein inhibitor of activated STAT, 2.
   
  0.526
LOC101074642
Protein inhibitor of activated STAT, 1a.
   
  0.526
ndufv2
NADH:ubiquinone oxidoreductase core subunit V2.
    
 
 0.513
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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