SH2B2 protein (Takifugu rubripes) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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[Homology]

Score

SH2B2

SH2B adaptor protein 2. (692 aa)

Predicted Functional Partners:

cblb

0.960

LOC101070370

0.960

cbl

0.960

LOC101074083

0.956

LOC101073316

0.659

LOC101068778

0.659

jak1

0.659

tyk2

0.659

grb2

0.625

LOC101061204

0.625

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101061204	LOC101068778	ENSTRUP00000049272	ENSTRUP00000043195	Uncharacterized protein.	Tyrosine-protein kinase.	0.579
LOC101061204	LOC101070370	ENSTRUP00000049272	ENSTRUP00000031224	Uncharacterized protein.	Uncharacterized protein.	0.856
LOC101061204	LOC101073316	ENSTRUP00000049272	ENSTRUP00000022494	Uncharacterized protein.	Tyrosine-protein kinase.	0.579
LOC101061204	LOC101074083	ENSTRUP00000049272	ENSTRUP00000074370	Uncharacterized protein.	Tyrosine-protein kinase receptor.	0.952
LOC101061204	SH2B2	ENSTRUP00000049272	ENSTRUP00000020679	Uncharacterized protein.	SH2B adaptor protein 2.	0.625
LOC101061204	cbl	ENSTRUP00000049272	ENSTRUP00000062750	Uncharacterized protein.	Cbl proto-oncogene, E3 ubiquitin protein ligase.	0.856
LOC101061204	cblb	ENSTRUP00000049272	ENSTRUP00000001230	Uncharacterized protein.	Cbl proto-oncogene B, E3 ubiquitin protein ligase.	0.856
LOC101061204	grb2	ENSTRUP00000049272	ENSTRUP00000020659	Uncharacterized protein.	Growth factor receptor-bound protein 2b.	0.903
LOC101061204	jak1	ENSTRUP00000049272	ENSTRUP00000057893	Uncharacterized protein.	Tyrosine-protein kinase.	0.579
LOC101061204	tyk2	ENSTRUP00000049272	ENSTRUP00000060023	Uncharacterized protein.	Tyrosine-protein kinase.	0.579
LOC101068778	LOC101061204	ENSTRUP00000043195	ENSTRUP00000049272	Tyrosine-protein kinase.	Uncharacterized protein.	0.579
LOC101068778	LOC101070370	ENSTRUP00000043195	ENSTRUP00000031224	Tyrosine-protein kinase.	Uncharacterized protein.	0.477
LOC101068778	LOC101073316	ENSTRUP00000043195	ENSTRUP00000022494	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.910
LOC101068778	SH2B2	ENSTRUP00000043195	ENSTRUP00000020679	Tyrosine-protein kinase.	SH2B adaptor protein 2.	0.659
LOC101068778	cbl	ENSTRUP00000043195	ENSTRUP00000062750	Tyrosine-protein kinase.	Cbl proto-oncogene, E3 ubiquitin protein ligase.	0.477
LOC101068778	cblb	ENSTRUP00000043195	ENSTRUP00000001230	Tyrosine-protein kinase.	Cbl proto-oncogene B, E3 ubiquitin protein ligase.	0.477
LOC101068778	grb2	ENSTRUP00000043195	ENSTRUP00000020659	Tyrosine-protein kinase.	Growth factor receptor-bound protein 2b.	0.579
LOC101068778	jak1	ENSTRUP00000043195	ENSTRUP00000057893	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.475
LOC101068778	tyk2	ENSTRUP00000043195	ENSTRUP00000060023	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.949
LOC101070370	LOC101061204	ENSTRUP00000031224	ENSTRUP00000049272	Uncharacterized protein.	Uncharacterized protein.	0.856