Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
nkd1NKD inhibitor of WNT signaling pathway 1. (445 aa)    
Predicted Functional Partners:
dvl3
Dishevelled segment polarity protein 3a.
    
 0.968
dvl2
Dishevelled segment polarity protein 2.
    
 0.968
dvl1
Dishevelled segment polarity protein 1a.
    
 0.968
ENSTRUP00000057963
annotation not available
    
 
 0.696
brd7
Bromodomain containing 7.
      
 0.607
sulf1
Sulfatase 1.
      
 0.563
rspry1
Ring finger and SPRY domain containing 1.
      
 0.562
H2S785_TAKRU
Sorting nexin 20.
      
 0.560
plekha8
Pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8.
      
 0.559
gpatch3
G patch domain containing 3.
      
 0.551
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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