Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
spoplSpeckle type BTB/POZ protein like b. (395 aa)    
Predicted Functional Partners:
cul3
Cullin 3a; Belongs to the cullin family.
   
 0.995
gli2
Uncharacterized protein.
   
 0.976
gli1
GLI family zinc finger 1.
   
 0.976
gli3
GLI family zinc finger 3.
   
 0.976
LOC101077858
GLI family zinc finger 2b.
   
 0.976
sufu
Suppressor of fused homolog.
     
 0.935
SPOP
Speckle type BTB/POZ protein.
  
  
 
0.901
cacul1
Cullin domain-containing protein; Belongs to the cullin family.
   
 0.881
LOC115248454
RING-box protein 1.
    
 0.855
LOC101079814
Ring-box 1, E3 ubiquitin protein ligase.
    
 0.855
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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