Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
BRK1BRICK1 subunit of SCAR/WAVE actin nucleating complex. (75 aa)    
Predicted Functional Partners:
cyfip1
Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.
    
 0.999
cyfip2
Cytoplasmic FMR1 interacting protein 2.
    
 0.998
nckap1
NCK-associated protein 1.
    
 0.996
nckap1l
NCK associated protein 1 like.
    
 0.995
LOC101069559
Abl-interactor 1b.
    
 0.992
ABI1
Abl-interactor 1a.
    
 0.992
wasf1
WASP family member 1.
    
 0.991
abi2
Abl-interactor 2b.
    
 0.987
wasf3
WASP family member 3b.
    
 0.986
H2V246_TAKRU
Uncharacterized protein.
    
 0.986
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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