TBX2 protein (Takifugu rubripes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

TBX2

T-box transcription factor 2. (680 aa)

Predicted Functional Partners:

foxp4

0.715

wnt3a

0.698

prox1

0.645

bmp4

0.644

nppa

0.643

gata4

0.622

rnf2

0.601

nkx2-5

0.567

uncx

0.533

fgfbp1

0.516

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
TBX2	bmp4	ENSTRUP00000020756	ENSTRUP00000049047	T-box transcription factor 2.	Bone morphogenetic protein 4.	0.644
TBX2	fgfbp1	ENSTRUP00000020756	ENSTRUP00000016815	T-box transcription factor 2.	Fibroblast growth factor binding protein 1b.	0.516
TBX2	foxp4	ENSTRUP00000020756	ENSTRUP00000061336	T-box transcription factor 2.	Forkhead box P4.	0.715
TBX2	gata4	ENSTRUP00000020756	ENSTRUP00000030652	T-box transcription factor 2.	GATA binding protein 4.	0.622
TBX2	nkx2-5	ENSTRUP00000020756	ENSTRUP00000027268	T-box transcription factor 2.	NK2 homeobox 5.	0.567
TBX2	nppa	ENSTRUP00000020756	ENSTRUP00000088156	T-box transcription factor 2.	Atrial natriuretic factor; Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Has a cGMP-stimulating activity (By similarity); Belongs to the natriuretic peptide family.	0.643
TBX2	prox1	ENSTRUP00000020756	ENSTRUP00000050090	T-box transcription factor 2.	Prospero homeobox 1a.	0.645
TBX2	rnf2	ENSTRUP00000020756	ENSTRUP00000056662	T-box transcription factor 2.	Ring finger protein 2.	0.601
TBX2	uncx	ENSTRUP00000020756	ENSTRUP00000034443	T-box transcription factor 2.	UNC homeobox.	0.533
TBX2	wnt3a	ENSTRUP00000020756	ENSTRUP00000084785	T-box transcription factor 2.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.698
bmp4	TBX2	ENSTRUP00000049047	ENSTRUP00000020756	Bone morphogenetic protein 4.	T-box transcription factor 2.	0.644
bmp4	fgfbp1	ENSTRUP00000049047	ENSTRUP00000016815	Bone morphogenetic protein 4.	Fibroblast growth factor binding protein 1b.	0.514
bmp4	gata4	ENSTRUP00000049047	ENSTRUP00000030652	Bone morphogenetic protein 4.	GATA binding protein 4.	0.869
bmp4	nkx2-5	ENSTRUP00000049047	ENSTRUP00000027268	Bone morphogenetic protein 4.	NK2 homeobox 5.	0.499
bmp4	wnt3a	ENSTRUP00000049047	ENSTRUP00000084785	Bone morphogenetic protein 4.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.750
fgfbp1	TBX2	ENSTRUP00000016815	ENSTRUP00000020756	Fibroblast growth factor binding protein 1b.	T-box transcription factor 2.	0.516
fgfbp1	bmp4	ENSTRUP00000016815	ENSTRUP00000049047	Fibroblast growth factor binding protein 1b.	Bone morphogenetic protein 4.	0.514
foxp4	TBX2	ENSTRUP00000061336	ENSTRUP00000020756	Forkhead box P4.	T-box transcription factor 2.	0.715
foxp4	prox1	ENSTRUP00000061336	ENSTRUP00000050090	Forkhead box P4.	Prospero homeobox 1a.	0.681
foxp4	uncx	ENSTRUP00000061336	ENSTRUP00000034443	Forkhead box P4.	UNC homeobox.	0.716