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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TBX2T-box transcription factor 2. (680 aa)    
Predicted Functional Partners:
nkx2-5
NK2 homeobox 5.
   
 
 0.693
wnt3a
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
    
 0.583
uncx
UNC homeobox.
    
 0.562
foxp4
Forkhead box P4.
    
 
 0.536
bmp4
Bone morphogenetic protein 4.
    
 0.506
greb1
Growth regulating estrogen receptor binding 1.
      
 0.455
serpinh1
Serpin peptidase inhibitor, clade H (heat shock protein 47), member 1b; Belongs to the serpin family.
      
 0.450
LOC101062006
Cdk5 and Abl enzyme substrate 2a; Belongs to the cyclin family.
      
 0.450
dlx1
Distal-less homeobox 1a.
    
 
 0.449
foxa1
Forkhead box A1.
    
 0.438
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.