Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LOC101070492Protein kinase domain-containing protein. (1222 aa)    
Predicted Functional Partners:
LOC101064673
Mitogen-activated protein kinase kinase 6.
  
 
0.932
MAP2K6
Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily.
    
0.928
yap1
Yes-associated protein 1.
    
 
 0.675
mapre1
Microtubule-associated protein, RP/EB family, member 1b.
    
 0.596
nudc
NudC nuclear distribution protein.
     
  0.546
bub1
BUB1 mitotic checkpoint serine/threonine kinase.
     
 0.545
plk3
Serine/threonine-protein kinase PLK.
     
  0.544
mad2l1
MAD2 mitotic arrest deficient-like 1 (yeast).
     
 0.539
rcc2
Regulator of chromosome condensation 2.
     
  0.535
LOC101077614
TPR_REGION domain-containing protein.
   
 
  0.531
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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