Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
rnf20E3 ubiquitin protein ligase. (1026 aa)    
Predicted Functional Partners:
ube2b
Ubiquitin-conjugating enzyme E2B (RAD6 homolog); Belongs to the ubiquitin-conjugating enzyme family.
    
 0.895
ube2a
Ubiquitin-conjugating enzyme E2A (RAD6 homolog); Belongs to the ubiquitin-conjugating enzyme family.
    
 0.895
leo1
LEO1 homolog, Paf1/RNA polymerase II complex component.
   
 0.890
cdc73
Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae).
   
 0.889
paf1
PAF1 homolog, Paf1/RNA polymerase II complex component.
    
 0.877
setd2
SET domain containing 2, histone lysine methyltransferase.
   
 
 0.868
LOC101072071
WW domain-containing protein.
   
 0.866
wac
WW domain containing adaptor with coiled-coil a.
   
 0.866
rps27a
Ribosomal protein S27a.
   
 0.857
uba52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
    
 0.833
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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