Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
H2T8N7_TAKRUIntegrase catalytic domain-containing protein. (614 aa)    
Predicted Functional Partners:
ENSTRUP00000055829
Uncharacterized protein.
   
 
 0.641
cd74
CD74 molecule, major histocompatibility complex, class II invariant chain a.
    
  0.633
Rps14
Ribosomal protein S14.
    
  0.633
pgbd5
PiggyBac transposable element derived 5.
   
 
 0.612
ENSTRUP00000064448
annotation not available
      
 0.582
rag1
V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...]
      
 0.515
galnt2
Polypeptide N-acetylgalactosaminyltransferase.
      
 0.510
tpr
Translocated promoter region b, nuclear basket protein.
    
  0.505
nup98
Nucleoporin 98.
    
  0.504
nup43
Nucleoporin 43.
    
  0.504
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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