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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ptk2bProtein tyrosine kinase 2 beta, b; Belongs to the protein kinase superfamily. Tyr protein kinase family. (990 aa)    
Predicted Functional Partners:
LOC101067972
Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.
  
  
 
0.902
nedd9
Neural precursor cell expressed, developmentally down-regulated 9.
    
 0.812
grb2
Growth factor receptor-bound protein 2b.
   
 0.787
LOC101061204
Uncharacterized protein.
   
 0.787
SOS1
SOS Ras/Rac guanine nucleotide exchange factor 1.
    
 0.739
sos2
Son of sevenless homolog 2 (Drosophila).
    
 0.739
TGFB1I1
Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways.
    
 0.702
PXN
Paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family.
    
 0.702
pxn
Uncharacterized protein.
    
 0.702
efs
Embryonal Fyn-associated substrate.
    
 0.702
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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