Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ptk2bProtein tyrosine kinase 2 beta, b; Belongs to the protein kinase superfamily. Tyr protein kinase family. (990 aa)    
Predicted Functional Partners:
LOC101067972
Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.
  
  
 
0.902
nedd9
Neural precursor cell expressed, developmentally down-regulated 9.
   
 0.887
grb2
Growth factor receptor-bound protein 2b.
   
 0.843
LOC101061204
Uncharacterized protein.
   
 0.843
efs
Embryonal Fyn-associated substrate.
   
 0.754
TGFB1I1
Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways.
    
 0.742
PXN
Paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family.
    
 0.742
pxn
Uncharacterized protein.
    
 0.742
LOC101061071
Leupaxin.
    
 0.742
SOS1
SOS Ras/Rac guanine nucleotide exchange factor 1.
    
 0.730
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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