Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
hspg2Heparan sulfate proteoglycan 2. (3494 aa)    
Predicted Functional Partners:
LOC101078584
Dystroglycan 1.
   
 0.986
LOC101073584
Peptidase S72 domain-containing protein.
   
 0.986
nid1
Nidogen 1a.
   
 0.874
ENSTRUP00000051666
Nidogen 2a (osteonidogen).
   
 0.874
tinagl1
Tubulointerstitial nephritis antigen like 1; Belongs to the peptidase C1 family.
   
 
 0.853
MUSK
Muscle associated receptor tyrosine kinase.
    
 0.780
LOC101063377
Decorin; May affect the rate of fibrils formation.
   
 
 0.728
LOC101078260
Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes.
   
 0.684
LOC101071044
Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes.
   
 0.684
FBLN2
Fibulin 1/2.
   
 0.680
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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