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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rfx6Regulatory factor X, 6. (947 aa)    
Predicted Functional Partners:
atr
ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.
    
 
 0.623
chek2
Checkpoint kinase 2.
   
 
 0.574
mnx1
Motor neuron and pancreas homeobox 1.
      
 0.566
ENSTRUP00000053907
Neurogenin 3.
   
  
 0.509
LOC101065226
Insulin-like.
     
 0.503
LOC105418820
Insulin.
     
 0.503
rfxap
Regulatory factor X-associated protein.
    
 
 0.492
fev
ETS domain-containing protein.
   
  
 0.453
rfxank
Regulatory factor X-associated ankyrin-containing protein.
   
 
 0.449
CCNK
Cyclin K; Belongs to the cyclin family.
   
  
 0.442
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.