Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
c20h1orf112Si:dkey-97o5.1. (919 aa)    
Predicted Functional Partners:
plk3
Serine/threonine-protein kinase PLK.
   
 
  0.959
fignl1
Fidgetin-like 1; Belongs to the AAA ATPase family.
   
 0.857
spast
Spastin; Belongs to the AAA ATPase family.
   
 0.829
fign
Fidgetin; Belongs to the AAA ATPase family.
   
 0.829
FIGNL2
Fidgetin like 2.
   
 0.829
ENSTRUP00000053212
Exonuclease 1.
   
 
 0.737
snrnp48
Small nuclear ribonucleoprotein 48 (U11/U12).
      
 0.705
rad51
DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]
   
 0.691
brca2
BRCA2 DNA repair associated.
   
 
 0.690
KATNAL2
Katanin catalytic subunit A1 like 2; Belongs to the AAA ATPase family.
   
 0.669
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
Server load: low (18%) [HD]